Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11931212 | 0.88 | CDK2 (0.44) | CHEK1CCNA2CDK2CCNA1NPC1 | |
| SCHEMBL14539507 | 0.87 | HTR1D (0.44) | CHEK1CCNA2CDK2CCNA1NPC1 | |
| SCHEMBL14539667 | 0.82 | SMPD3 (0.41) | CHEK1CCNA2CDK2CCNA1ADORA2A | |
| SCHEMBL14545940 | 0.81 | SMPD3 (0.40) | CHEK1CCNA2CDK2CCNA1ADORA2A | |
| SCHEMBL14539666 | 0.79 | SMPD3 (0.39) | CHEK1CCNA2CDK2CCNA1ADORA2A | |
| SCHEMBL11931287 | 0.78 | CKS1B (0.49) | — | |
| SCHEMBL11931284 | 0.71 | CDK2 (0.55) | CHEK1CCNA2CDK2CCNA1NPC1 | |
| SCHEMBL11931290 | 0.71 | AKT1 (0.37) | CHEK1CCNA2CDK2CCNA1KDR | |
| SCHEMBL11930846 | 0.70 | ABL1 (0.38) | CHEK1CCNA2CDK2CCNA1KDR | |
| SCHEMBL11930847 | 0.70 | ABL1 (0.38) | CHEK1CCNA2CDK2CCNA1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041712-A1 | PYRAZOLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |