Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540419 | 0.86 | CNR1 (0.75) | CNR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13135224 | 0.86 | CNR1 (0.51) | CNR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3550472 | 0.82 | CNR1 (0.51) | CNR1CYP3A4CYP2C9CYP2C19P2RX3 | |
| SCHEMBL13114629 | 0.82 | CNR1 (0.75) | CNR1CYP3A4CYP2C9CYP2C19NR1H2 | |
| SCHEMBL14540568 | 0.82 | CNR1 (0.72) | CNR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14540423 | 0.82 | CNR1 (0.56) | CNR1CYP3A4CYP2C9CYP2C19NR1H2 | |
| SCHEMBL14540421 | 0.81 | CNR1 (0.60) | CNR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14540718 | 0.80 | CNR1 (0.54) | CNR1CYP3A4CYP2C9CYP2C19NR1H2 | |
| SCHEMBL13114630 | 0.80 | CNR1 (0.65) | CNR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13114639 | 0.78 | CNR1 (0.73) | CNR1CYP3A4CYP2C9CYP2C19NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697371-B1 | AZABICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2007-04-25 | — | — | EP | disclosed |