Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 16/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903074 | 1.00 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3NQO2 | |
| SCHEMBL911675 | 1.00 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3NQO2 | |
| SCHEMBL12903064 | 0.82 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3NQO2 | |
| SCHEMBL911585 | 0.82 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3NQO2 | |
| SCHEMBL910931 | 0.80 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL910932 | 0.80 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL911509 | 0.77 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL911510 | 0.77 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL12903075 | 0.75 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL911360 | 0.75 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039563-A1 | 9-AZABICYCLO [3 . 3 . 1] NONANE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS | N.V. ORGANON (NL) | 2007-04-12 | — | — | WO | disclosed |