Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.61 |
| ▸ | CDK2 | P24941 | 12/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953754 | 0.87 | CDK2 (0.75) | GSK3BCDK2CCNE1CCNA2CCNA1 | |
| SCHEMBL14418683 | 0.86 | GSK3B (0.76) | GSK3BCDK2CCNE1 | |
| SCHEMBL14418674 | 0.80 | GSK3B (0.53) | GSK3BCDK2CCNE1CCNA2CCNA1 | |
| SCHEMBL14613394 | 0.80 | GSK3B (0.69) | GSK3BCDK2CCNE1CCNA2CCNA1 | |
| SCHEMBL14607083 | 0.78 | CDK2 (0.62) | GSK3BCDK2CCNE1CCNA2CCNA1 | |
| SCHEMBL14418798 | 0.78 | GSK3B (0.53) | GSK3BCDK2CCNE1CCNA2CCNA1 | |
| SCHEMBL12953716 | 0.77 | CDK2 (0.75) | GSK3BCDK2CCNE1CCNA2CCNA1 | |
| SCHEMBL12953026 | 0.77 | CDK2 (0.81) | GSK3BCDK2CCNE1CCNA2CCNA1 | |
| SCHEMBL13122670 | 0.77 | CDK2 (0.78) | GSK3BCDK2CCNE1CCNA2CCNA1 | |
| SCHEMBL12954227 | 0.76 | GSK3B (0.76) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |