Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12954083 | 0.85 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL13118871 | 0.77 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119103 | 0.75 | GSK3B (0.70) | GSK3BCDK2CCNE1 | |
| SCHEMBL14050841 | 0.75 | GSK3B (0.49) | GSK3BSMN1; SMN2CDK2CCNE1MEN1 | |
| SCHEMBL12953714 | 0.75 | GSK3B (0.64) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119082 | 0.73 | GSK3B (0.67) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119038 | 0.73 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119099 | 0.73 | GSK3B (0.66) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952884 | 0.72 | GSK3B (0.73) | GSK3BCDK2CCNE1 | |
| SCHEMBL14418838 | 0.72 | GSK3B (0.65) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |