Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 5/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14607258 | 0.91 | GSK3B (0.57) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14050830 | 0.87 | GSK3B (0.68) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL14545282 | 0.87 | GSK3B (0.64) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13122118 | 0.81 | GSK3B (0.67) | GSK3BCDK2CCNE1 | |
| SCHEMBL13304607 | 0.79 | GSK3B (0.79) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13304919 | 0.78 | GSK3B (0.62) | GSK3BCHEK1CDK2CCNE1 | |
| SCHEMBL13122091 | 0.78 | GSK3B (0.82) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122098 | 0.78 | GSK3B (0.84) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122117 | 0.78 | GSK3B (0.78) | GSK3BCDK2CCNE1 | |
| SCHEMBL13304983 | 0.78 | GSK3B (0.61) | GSK3BCHEK1CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |