Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | CDH1 | P12830 | 1/20 | 0.40 |
| ▸ | APC | P25054 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810770 | 0.80 | CNR1 (0.54) | CNR1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL22532587 | 0.80 | CNR1 (0.44) | CNR1GAAADORA2AKMT2AMEN1 | |
| SCHEMBL2036410 | 0.79 | CKS1B (0.53) | CNR1LMNAL3MBTL1ADORA2AKMT2A | |
| SCHEMBL30478423 | 0.79 | CKS1B (0.53) | CNR1LMNAL3MBTL1ADORA2AKMT2A | |
| SCHEMBL4693817 | 0.79 | KDM4E (0.48) | CNR1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL10511681 | 0.76 | ADORA2A (0.46) | CNR1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL14545305 | 0.76 | ADORA2A (0.56) | CNR1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL5943078 | 0.76 | CNR1 (0.46) | CNR1KDM4EGAALMNAL3MBTL1 | |
| SCHEMBL5773432 | 0.74 | CNR1 (0.62) | CNR1CDH1APCCTNNB1TCF7L2 | |
| SCHEMBL4252470 | 0.74 | CNR1 (0.58) | CNR1KDM4EGAALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078135-A1 | Substituted heteroaryl CB1 antagonists | NEUROGEN CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078135-A1 | Substituted heteroaryl CB1 antagonists | CNR1, CNR2, OPRL1 | CNR1 1/4885KDM4E 1408/4885GAA 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.