Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.60 |
| ▸ | GSK3B | P49841 | 14/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14545218 | 0.87 | GSK3B (0.59) | CDK2GSK3BCCNE1 | |
| SCHEMBL14582509 | 0.87 | CDK2 (0.59) | CDK2GSK3BCCNE1 | |
| SCHEMBL14418670 | 0.85 | CDK2 (0.58) | CDK2GSK3BCCNE1 | |
| SCHEMBL14628933 | 0.85 | CDK2 (0.58) | CDK2GSK3BCCNE1 | |
| SCHEMBL14411150 | 0.85 | CDK2 (0.60) | CDK2GSK3BCCNE1 | |
| SCHEMBL12952928 | 0.85 | CDK2 (0.60) | CDK2GSK3BCCNE1 | |
| SCHEMBL12953198 | 0.80 | CDK2 (0.64) | CDK2GSK3BCCNE1 | |
| SCHEMBL12953897 | 0.80 | CDK2 (0.64) | CDK2GSK3BCCNE1 | |
| SCHEMBL14559626 | 0.79 | CDK2 (0.68) | CDK2GSK3BCCNE1 | |
| SCHEMBL13122816 | 0.79 | CDK2 (0.73) | CDK2GSK3BCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |