Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.51 |
| ▸ | GSK3B | P49841 | 14/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14043286 | 0.84 | GSK3B (0.70) | CDK2GSK3BCCNE1 | |
| SCHEMBL14560144 | 0.82 | CDK2 (0.56) | CDK2GSK3BCCNE1 | |
| SCHEMBL14043174 | 0.80 | CDK2 (0.52) | CDK2GSK3B | |
| SCHEMBL12953334 | 0.76 | CCNT1 (0.37) | CDK2GSK3BCCNE1 | |
| SCHEMBL12954201 | 0.75 | GSK3B (0.53) | CDK2GSK3BCCNE1 | |
| SCHEMBL13288589 | 0.74 | CCNT1 (0.37) | CDK2GSK3BCCNE1 | |
| SCHEMBL12954087 | 0.72 | GSK3B (0.49) | CDK2GSK3BCCNE1 | |
| SCHEMBL13146301 | 0.72 | GSK3B (0.49) | CDK2GSK3BCCNE1 | |
| SCHEMBL13118130 | 0.71 | CDK2 (0.69) | CDK2GSK3BCCNE1 | |
| SCHEMBL13288598 | 0.69 | CDK2 (0.50) | CDK2GSK3BCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| US-7196078-B2 | Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPOARTION (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196078-B2 | Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPOARTION (US) | 2007-03-27 | — | — | US | disclosed |