Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.66 |
| ▸ | CDK2 | P24941 | 9/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119209 | 0.92 | GSK3B (0.64) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119165 | 0.92 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119258 | 0.91 | GSK3B (0.62) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119228 | 0.90 | GSK3B (0.63) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954402 | 0.90 | GSK3B (0.63) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954399 | 0.90 | GSK3B (0.63) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119232 | 0.90 | GSK3B (0.66) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119206 | 0.89 | GSK3B (0.62) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119166 | 0.89 | GSK3B (0.67) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119229 | 0.89 | GSK3B (0.67) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |