Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.56 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | PYGM | P11217 | 3/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | CDA | P32320 | 2/20 | 0.44 |
| ▸ | TK2 | O00142 | 2/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42101 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 | |
| SCHEMBL13423825 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 | |
| SCHEMBL7152755 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 | |
| SCHEMBL12143115 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 | |
| SCHEMBL12143539 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 | |
| SCHEMBL14146449 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 | |
| SCHEMBL42102 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 | |
| Phosphoric Acid SCHEMBL15522443 | 0.95 | SLC28A1 (0.52) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 | |
| SCHEMBL7146490 | 0.94 | SLC28A1 (0.51) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 | |
| SCHEMBL29623888 | 0.87 | CDK1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931691-B1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIV HEALTH NETWORK (CA) | 2013-08-21 | — | — | EP | disclosed |
| WO-2007038859-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | disclosed |