Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.81 |
| ▸ | IDO1 | P14902 | 2/20 | 0.65 |
| ▸ | AGXT | P21549 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13263642 | 0.92 | MAOB (0.79) | MAOBIDO1AGXTRAB9ASMN1; SMN2 | |
| SCHEMBL171916 | 0.91 | MAOB (0.73) | MAOBIDO1AGXTRAB9ASMN1; SMN2 | |
| SCHEMBL14854755 | 0.90 | MAOB (0.77) | MAOBIDO1AGXTRAB9ASMN1; SMN2 | |
| SCHEMBL4412216 | 0.90 | MAOB (0.77) | MAOBIDO1AGXTRAB9ASMN1; SMN2 | |
| SCHEMBL1680537 | 0.90 | MAOB (1.00) | MAOBIDO1AGXTBCHE | |
| SCHEMBL21260547 | 0.90 | MAOB (0.73) | MAOBIDO1AGXTRAB9ASMN1; SMN2 | |
| SCHEMBL16710547 | 0.87 | MAOB (0.71) | MAOBIDO1AGXTRAB9AMRGPRX4 | |
| SCHEMBL21340758 | 0.87 | MAOB (0.68) | MAOBIDO1AGXTRAB9ASMN1; SMN2 | |
| SCHEMBL4412215 | 0.87 | MAOB (0.68) | MAOBIDO1AGXTRAB9ASMN1; SMN2 | |
| SCHEMBL29304364 | 0.87 | MAOB (0.68) | MAOBIDO1AGXTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007040682-A1 | BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS EHF. (IS) | 2007-04-12 | — | — | WO | disclosed |