Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 4/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.48 |
| ▸ | LCK | P06239 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14548735 | 0.97 | MAPT (0.53) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL14548726 | 0.87 | RXFP1 (0.53) | MAPTMEN1KMT2AHTTKCNK3 | |
| SCHEMBL14548733 | 0.87 | MAPT (0.48) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL12333075 | 0.87 | MAPT (0.57) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL2456844 | 0.86 | MAPT (0.56) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL12333076 | 0.85 | MAPT (0.57) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL2459047 | 0.84 | MAPT (0.56) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL2462026 | 0.83 | MAPT (0.53) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL14548725 | 0.83 | RXFP1 (0.53) | MAPTMEN1KMT2AHTTKCNK3 | |
| SCHEMBL14548734 | 0.83 | MAPT (0.48) | MAPTMEN1KMT2AHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349836-B2 | Phthalazine derivatives as inhibitors of protein kinase | ARALDI GIAN-LUCA (US) | 2013-01-08 | — | — | US | disclosed |