Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861481 | 0.94 | JAK2 (0.58) | JAK2KCNH2 | |
| SCHEMBL3501915 | 0.83 | JAK2 (0.58) | JAK2 | |
| SCHEMBL13248917 | 0.81 | JAK2 (0.52) | JAK2 | |
| SCHEMBL14548738 | 0.80 | JAK2 (0.48) | JAK2 | |
| SCHEMBL3501108 | 0.80 | JAK2 (0.55) | JAK2 | |
| SCHEMBL14548750 | 0.80 | JAK2 (0.46) | JAK2 | |
| SCHEMBL2867451 | 0.79 | JAK2 (0.61) | JAK2KCNH2 | |
| SCHEMBL2858014 | 0.78 | JAK2 (0.53) | JAK2 | |
| SCHEMBL2867519 | 0.78 | JAK2 (0.58) | JAK2KCNH2 | |
| SCHEMBL11981754 | 0.76 | JAK2 (0.51) | JAK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349865-B2 | Inhibitors of janus kinases | MERCK SHARP & DOHME CORP. (US) | 2013-01-08 | — | — | US | disclosed |