Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130095 | 0.86 | TDP1 (0.48) | HDAC1HDAC2TDP1HTTPDE4A | |
| SCHEMBL7906492 | 0.84 | PDE4A (0.49) | HDAC1HDAC2TDP1HTTPDE4A | |
| SCHEMBL8421549 | 0.82 | PDE4A (0.47) | HDAC1HDAC2TDP1HTTPDE4A | |
| SCHEMBL6690200 | 0.82 | TDP1 (0.49) | HDAC1HDAC2TDP1HTTPDE4A | |
| SCHEMBL6803674 | 0.81 | HDAC1 (0.46) | HDAC1HDAC2TDP1HTTPDE4A | |
| SCHEMBL14548981 | 0.80 | MEN1 (0.42) | HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9435466 | 0.80 | CCNE2 (0.47) | HDAC1HDAC2TDP1HTTPDE4A | |
| SCHEMBL13609069 | 0.79 | HTT (0.57) | HDAC1HDAC2TDP1HTTPDE4A | |
| SCHEMBL13196022 | 0.78 | NPC1 (0.45) | HDAC1HDAC2TDP1HTTPDE4A | |
| SCHEMBL11986874 | 0.78 | CDK1 (0.59) | PDE4APDE4BPDE4CPDE4DTMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189941-B1 | NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS | IPSEN PHARMA (FR) | 2013-01-09 | — | — | EP | disclosed |