⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453495 | 0.85 | — | — | |
| SCHEMBL1454971 | 0.77 | TSHR (0.42) | — | |
| SCHEMBL3114798 | 0.76 | — | — | |
| SCHEMBL31716980 | 0.76 | — | — | |
| SCHEMBL1452894 | 0.73 | TSHR (0.37) | — | |
| SCHEMBL387573 | 0.72 | — | — | |
| SCHEMBL1454894 | 0.72 | — | — | |
| SCHEMBL21558772 | 0.71 | TSHR (0.46) | — | |
| SCHEMBL757068 | 0.71 | — | — | |
| SCHEMBL2133109 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910617-B2 | Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound | SANKYO COMPANY, LIMITED (JP) | 2011-03-22 | — | — | US | disclosed |
| CN-1921847-B | Amino alcohol compound | SANKYO CO | 2010-06-16 | — | — | CN | disclosed |
| US-20070191468-A1 | Amino alcohol compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-08-16 | — | — | US | disclosed |
| CN-1921847-A | Amino alcohol compound | SANKYO CO (JP) | 2007-02-28 | — | — | CN | disclosed |
| EP-1733724-A1 | AMINO ALCOHOL COMPOUND | Sankyo Company, Limited (JP) | 2006-12-20 | — | — | EP | disclosed |