SCHEMBL14550140

SCHEMBL14550140

C[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN(CC(=O)O)CC(=O)O)C(=O)N[C@@H](CCCCNC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCCc1nnn[nH]1)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.42
▸ CCKAR P32238 12/20 0.37
▸ CCKBR P32239 12/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14550233 0.95 GLP1R (0.42) GLP1RCCKARCCKBR
SCHEMBL14550155 0.95 GLP1R (0.42) GLP1RCCKARCCKBR
SCHEMBL14550218 0.92 GLP1R (0.40) GLP1RCCKARCCKBR
SCHEMBL14550210 0.90 GLP1R (0.41) GLP1RCCKARCCKBR
SCHEMBL14550491 0.90 GLP1R (0.41) GLP1RCCKARCCKBR
SCHEMBL14550130 0.90 GLP1R (0.41) GLP1RCCKARCCKBR
SCHEMBL14550116 0.90 GLP1R (0.39) GLP1RCCKARCCKBR
SCHEMBL14550254 0.89 GLP1R (0.42) GLP1RCCKARCCKBR
SCHEMBL14550122 0.88 GLP1R (0.41) GLP1RCCKARCCKBR
SCHEMBL14550224 0.87 GLP1R (0.40) GLP1RCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R GLP1R 5/4885CCKAR 40/4885CCKBR 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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