Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 17/20 | 0.49 |
| ▸ | USP47 | Q96K76 | 16/20 | 0.49 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455918 | 0.92 | USP7 (0.50) | USP7USP47PADI4MEN1MAPT | |
| SCHEMBL1455311 | 0.80 | P2RX1 (0.43) | MEN1MAPTKMT2ARAB9A | |
| SCHEMBL2680616 | 0.80 | USP7 (0.75) | USP7USP47 | |
| SCHEMBL1454774 | 0.77 | MEN1 (0.51) | USP7USP47MEN1MAPTKMT2A | |
| SCHEMBL4976935 | 0.77 | USP47 (0.62) | USP7USP47PADI4MEN1MAPT | |
| SCHEMBL1455618 | 0.75 | NPC1 (0.43) | MEN1MAPTKMT2ARAB9A | |
| SCHEMBL2680491 | 0.72 | USP7 (0.78) | USP7USP47 | |
| SCHEMBL2681089 | 0.71 | USP7 (0.77) | USP7USP47PADI4MAPT | |
| SCHEMBL1455594 | 0.70 | USP7 (0.55) | USP7USP47PADI4MEN1MAPT | |
| SCHEMBL1454559 | 0.70 | PDE7A (0.54) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2012-01-18 | — | — | EP | disclosed |
| US-7910595-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2011-03-22 | — | — | US | disclosed |