Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.49 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BMI1 | P35226 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14552137 | 1.00 | ESR2 (0.50) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL12937170 | 0.95 | ESR2 (0.55) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL14552149 | 0.92 | ESR2 (0.50) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL22507247 | 0.90 | SIRT2 (0.45) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL13231652 | 0.89 | ESR2 (0.60) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL15875798 | 0.86 | ESR2 (0.67) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL12130074 | 0.85 | GRIA1 (0.67) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL14552171 | 0.85 | ESR1 (0.43) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL16435317 | 0.85 | ESR1 (0.49) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL16435340 | 0.84 | ESR1 (0.48) | ESR2ESR1GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785002-B1 | High-energy triplet host materials, luminescent layer comprising the same, and organic electroluminescent device comprising the luminescent layer | BOWLING GREEN STATE UNIVERSITY (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130009137-A1 | VERTICALLY PHASE-SEPARATING SEMICONDUCTING ORGANIC MATERIAL LAYERS | PLEXTRONICS, INC. | 2013-01-10 | — | — | US | disclosed |