Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | KLK1 | P06870 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3838146 | 0.90 | F10 (0.61) | F10F2KLK1 | |
| SCHEMBL1455580 | 0.88 | F10 (0.73) | F10F2KLK1 | |
| SCHEMBL1456139 | 0.87 | F10 (0.72) | F10F2KLK1 | |
| SCHEMBL3837648 | 0.86 | F10 (0.65) | F10F2KLK1 | |
| SCHEMBL3833104 | 0.86 | F10 (0.69) | F10F2KLK1 | |
| SCHEMBL1455650 | 0.85 | F10 (0.73) | F10F2KLK1 | |
| SCHEMBL1456597 | 0.85 | F10 (0.77) | F10F2KLK1 | |
| SCHEMBL1456038 | 0.85 | F10 (0.80) | F10F2KLK1 | |
| SCHEMBL1456259 | 0.85 | F10 (0.77) | F10F2KLK1 | |
| SCHEMBL3838721 | 0.85 | F10 (0.71) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910606-B2 | Pyrazole-derivatives as factor Xa inhibitors | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-03-22 | — | — | US | claimed |
| US-7910606-B2 | Pyrazole-derivatives as factor Xa inhibitors | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-03-22 | — | — | US | disclosed |
| EP-1581523-A1 | PYRAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004056815-A1 | PYRAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-08 | — | — | WO | disclosed |