Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5338412 | 0.89 | IKBKB (0.75) | IKBKB | |
| SCHEMBL5337743 | 0.88 | IKBKB (0.82) | IKBKB | |
| SCHEMBL5341043 | 0.87 | IKBKB (0.73) | IKBKB | |
| SCHEMBL5341703 | 0.86 | IKBKB (0.74) | IKBKB | |
| SCHEMBL5349338 | 0.86 | IKBKB (0.77) | IKBKB | |
| SCHEMBL5339928 | 0.86 | IKBKB (0.79) | IKBKB | |
| SCHEMBL5341540 | 0.85 | IKBKB (0.76) | IKBKB | |
| SCHEMBL5341269 | 0.85 | IKBKB (0.70) | IKBKB | |
| SCHEMBL5337309 | 0.85 | IKBKB (0.76) | IKBKB | |
| SCHEMBL5336628 | 0.85 | IKBKB (0.69) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186743-B2 | Substituted pyrazolyl compounds for the treatment of inflammation | PHARMACIA CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186743-B2 | Substituted pyrazolyl compounds for the treatment of inflammation | PHARMACIA CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |