Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.64 |
| ▸ | F2 | P00734 | 5/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456108 | 0.90 | F10 (0.63) | F10F2 | |
| SCHEMBL3837002 | 0.88 | F10 (0.58) | F10F2PLATKLK1 | |
| SCHEMBL1455393 | 0.88 | F10 (0.62) | F10F2KLK1 | |
| SCHEMBL1456127 | 0.87 | F10 (0.68) | F10F2PLATKLK1 | |
| SCHEMBL3834004 | 0.83 | F10 (0.58) | F10F2PLATKLK1 | |
| SCHEMBL3838120 | 0.81 | F10 (0.57) | F10F2PLATKLK1 | |
| SCHEMBL2783165 | 0.79 | PTGER1 (0.45) | F10F2 | |
| SCHEMBL1455285 | 0.79 | F10 (0.67) | F10F2KLK1 | |
| SCHEMBL1675236 | 0.78 | F10 (1.00) | F10F2PLATKLK1 | |
| SCHEMBL1456206 | 0.78 | F10 (0.69) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910606-B2 | Pyrazole-derivatives as factor Xa inhibitors | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-03-22 | — | — | US | claimed |
| US-7910606-B2 | Pyrazole-derivatives as factor Xa inhibitors | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-03-22 | — | — | US | disclosed |