Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.62 |
| ▸ | CDK2 | P24941 | 15/20 | 0.61 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953507 | 0.88 | GSK3B (0.69) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL12953764 | 0.87 | GSK3B (0.67) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL12953016 | 0.87 | GSK3B (0.67) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL12954287 | 0.84 | GSK3B (0.68) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL12953523 | 0.84 | GSK3B (0.61) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL12953012 | 0.83 | GSK3B (0.74) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL12953524 | 0.83 | GSK3B (0.77) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL12954199 | 0.82 | GSK3B (0.73) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL12953490 | 0.82 | GSK3B (0.81) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL12953663 | 0.82 | GSK3B (0.72) | GSK3BCDK2CCNA2CCNA1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196078-B2 | Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPOARTION (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196078-B2 | Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPOARTION (US) | 2007-03-27 | — | — | US | disclosed |