Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.77 |
| ▸ | PPARG | P37231 | 17/20 | 0.77 |
| ▸ | PPARD | Q03181 | 8/20 | 0.77 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366555 | 1.00 | PPARA (0.77) | PPARAPPARGPPARDACACB | |
| SCHEMBL5380825 | 0.89 | PPARG (0.72) | PPARAPPARGPPARD | |
| SCHEMBL5382474 | 0.88 | PPARG (0.92) | PPARAPPARGPPARD | |
| SCHEMBL5382488 | 0.88 | PPARG (0.92) | PPARAPPARGPPARD | |
| SCHEMBL5380701 | 0.87 | PPARG (0.95) | PPARAPPARGPPARD | |
| Naveglitazar SCHEMBL677199 | 0.87 | PPARG (1.00) | PPARAPPARGPPARD | |
| Naveglitazar SCHEMBL5374978 | 0.87 | PPARG (1.00) | PPARAPPARGPPARD | |
| Naveglitazar SCHEMBL2827844 | 0.87 | PPARG (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5375538 | 0.86 | PPARG (0.79) | PPARAPPARGPPARD | |
| Naveglitazar SCHEMBL5383187 | 0.86 | PPARG (0.97) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |