SCHEMBL1456089

SCHEMBL1456089

SCCn1cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3021112 0.81
SCHEMBL7529371 0.79 TP53 (0.39)
SCHEMBL27910344 0.78 TP53 (0.53)
SCHEMBL4453519 0.77 TP53 (0.37)
SCHEMBL4451148 0.77 TP53 (0.37)
SCHEMBL4447375 0.77 TP53 (0.37)
SCHEMBL963588 0.77 TP53 (0.37)
SCHEMBL1680345 0.72
SCHEMBL20465806 0.72 TP53 (0.48)
SCHEMBL691481 0.72 TP53 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431313-A Antifungal compound, preparation method and application thereof 上海交通大学 2025-02-14 CN disclosed
US-8920870-B2 Variable stiffness catheter assembly BOSTON SCIENTIFIC SCIMED, INC. (US) 2014-12-30 US disclosed
US-8556955-B2 Adjustable bifurcation catheter incorporating electroactive polymer and methods of makings and using the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-10-15 US disclosed
EP-2051765-B1 CATHETERS HAVING ACTUATABLE LUMEN ASSEMBLIES BOSTON SCIENT LTD (BB) 2013-06-26 EP disclosed
US-8439961-B2 Stent retaining mechanisms BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-05-14 US disclosed
US-8414632-B2 Adjustable catheter tip BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-04-09 US disclosed
US-8398693-B2 Electrically actuated medical devices BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-03-19 US disclosed
US-20120265286-A1 ADJUSTABLE BIFURCATION CATHETER INCORPORATING ELECTROACTIVE POLYMER AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-10-18 US disclosed
US-8206429-B2 Adjustable bifurcation catheter incorporating electroactive polymer and methods of making and using the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-06-26 US disclosed
EP-1937190-B1 BIFURCATED STENT BOSTON SCIENT LTD (BB) 2012-06-20 EP disclosed
EP-0757051-A1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME SUNTORY LIMITED (JP) 1997-02-05 EP disclosed
EP-0272694-B1 2-DITHIOALKYL-DIHYDROPYRIDINES, A METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1992-03-18 EP disclosed
US-5021436-A Antiulcer, anticoagulant, antiischaemic agent BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) 1991-06-04 US disclosed
US-4999362-A Hypotensive, Antiulcer, Cytoprotective, Antithrombotic Agents BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1991-03-12 US disclosed
US-4918087-A 2-thiomethyl-substituted-pyridine and -3,5-dicarboxylates having anti-hypertensive activity BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1990-04-17 US disclosed
EP-0282904-A2 2-Thiomethyl-substituted-pyridines, a method for their preparation and pharmaceutical compositions containing them BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1988-09-21 EP disclosed
EP-0272694-A1 2-Dithioalkyl-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1988-06-29 EP disclosed
EP-0233228-A1 PHARMACEUTICALLY ACTIVE 2-THIOMETHYL-SUBSTITUTED-1,4-DIHYDROPYRIDINES BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1987-08-26 EP disclosed
WO-1987000836-A1 PHARMACEUTICALLY ACTIVE 2-THIOMETHYL-SUBSTITUTED-1,4-DIHYDROPYRIDINES BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1987-02-12 WO disclosed
US-3980089-A Novel heterocyclic flavoring compositions and processes INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-09-14 US disclosed