Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 14/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13350368 | 0.85 | PPARG (0.42) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL13350393 | 0.80 | FFAR1 (0.39) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL3553563 | 0.80 | PPARG (0.47) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL3553559 | 0.80 | PPARG (0.47) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL3555152 | 0.80 | PPARG (0.47) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL13350413 | 0.80 | PPARG (0.41) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL13350369 | 0.79 | FFAR1 (0.41) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL13350351 | 0.79 | FFAR1 (0.41) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL13350350 | 0.78 | FFAR1 (0.41) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL13350450 | 0.77 | FFAR1 (0.41) | PPARGFFAR1CYP26A1CYP26B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007033002-A1 | CONFORMATIONALLY CONSTRAINED 3- (4-HYDROXY-PHENYL) - SUBSTITUTED-PROPANOIC ACIDS USEFUL FOR TREATING METABOLIC DISORDERS | AMGEN INC. (US) | 2007-03-22 | — | — | WO | disclosed |