Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 19/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616818 | 1.00 | FFAR1 (0.75) | FFAR1CYP2C9CYP2B6SLCO1B3 | |
| SCHEMBL3854725 | 1.00 | FFAR1 (0.75) | FFAR1CYP2C9CYP2B6SLCO1B3 | |
| SCHEMBL13616704 | 0.90 | FFAR1 (0.61) | FFAR1CYP2C9CYP2B6SLCO1B3 | |
| SCHEMBL14567332 | 0.90 | FFAR1 (0.61) | FFAR1CYP2C9CYP2B6SLCO1B3 | |
| SCHEMBL3861321 | 0.90 | FFAR1 (0.78) | FFAR1 | |
| SCHEMBL13616832 | 0.90 | FFAR1 (0.78) | FFAR1 | |
| SCHEMBL14567233 | 0.88 | FFAR1 (0.75) | FFAR1 | |
| SCHEMBL3856226 | 0.88 | FFAR1 (0.75) | FFAR1 | |
| SCHEMBL3859131 | 0.88 | FFAR1 (0.75) | FFAR1 | |
| SCHEMBL3852420 | 0.88 | FFAR1 (0.75) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007033002-A1 | CONFORMATIONALLY CONSTRAINED 3- (4-HYDROXY-PHENYL) - SUBSTITUTED-PROPANOIC ACIDS USEFUL FOR TREATING METABOLIC DISORDERS | AMGEN INC. (US) | 2007-03-22 | — | — | WO | disclosed |