Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.65 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.65 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.65 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14567889 | 0.93 | HSP90AA1 (0.66) | HSP90AA1HSP90B1TRAP1HSP90AB1 | |
| SCHEMBL14567890 | 0.91 | HSP90AA1 (0.63) | HSP90AA1HSP90B1TRAP1HSP90AB1 | |
| SCHEMBL312056 | 0.89 | HSP90AA1 (0.81) | HSP90AA1HSP90B1TRAP1HSP90AB1 | |
| SCHEMBL14567886 | 0.89 | HSP90AA1 (0.81) | HSP90AA1HSP90B1TRAP1HSP90AB1 | |
| SCHEMBL14568083 | 0.87 | HSP90AA1 (0.80) | HSP90AA1HSP90B1TRAP1HSP90AB1 | |
| SCHEMBL14567885 | 0.86 | HSP90AA1 (0.64) | HSP90AA1HSP90B1TRAP1HSP90AB1 | |
| SCHEMBL14568086 | 0.83 | HSP90AA1 (0.72) | HSP90AA1HSP90B1TRAP1HSP90AB1 | |
| SCHEMBL10185695 | 0.82 | HSP90AA1 (0.66) | HSP90AA1HSP90B1TRAP1HSP90AB1 | |
| SCHEMBL14567892 | 0.82 | HSP90AA1 (0.82) | HSP90AA1HSP90B1TRAP1HSP90AB1 | |
| SCHEMBL313144 | 0.82 | HSP90AA1 (0.78) | HSP90AA1HSP90B1TRAP1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007035963-A2 | ANTI-TUMOR METHODS USING MULTI DRUG RESISTANCE INDEPENDENT SYNTHETIC HSP90 INHIBITORS | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-03-29 | — | — | WO | disclosed |