Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066170 | 0.75 | ADORA2A (0.50) | HDAC6LTA4HHDAC1KDM4EADORA2A | |
| SCHEMBL2010867 | 0.74 | HDAC6 (0.43) | HDAC6LTA4HHDAC1 | |
| SCHEMBL21357355 | 0.74 | HDAC6 (0.40) | HDAC6LTA4HHDAC1 | |
| SCHEMBL8022021 | 0.74 | HDAC6 (0.40) | HDAC6LTA4HHDAC1 | |
| SCHEMBL5803499 | 0.74 | HDAC6 (0.40) | HDAC6LTA4HHDAC1 | |
| SCHEMBL15645058 | 0.74 | HDAC6 (0.40) | HDAC6LTA4HHDAC1 | |
| SCHEMBL2010864 | 0.74 | HDAC6 (0.40) | HDAC6LTA4HHDAC1 | |
| SCHEMBL277149 | 0.74 | HDAC6 (0.43) | HDAC6LTA4HHDAC1 | |
| SCHEMBL277148 | 0.74 | HDAC6 (0.46) | HDAC6LTA4HHDAC1 | |
| SCHEMBL6265346 | 0.74 | HDAC6 (0.37) | HDAC6LTA4HHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742641-A | CAS12A endonuclease variants and methods of use | 安索玛私人有限责任公司 | 2024-10-01 | — | — | CN | claimed |
| WO-2024149841-A1 | DETECTION OF MODIFIED NUCLEOBASES IN DNA SAMPLES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-18 | — | — | WO | claimed |
| WO-2024083982-A1 | DETECTION OF MODIFIED NUCLEOBASES IN NUCLEIC ACID SAMPLES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-04-25 | — | — | WO | claimed |
| CN-117659207-A | Double-base editing system and application thereof | 广州医科大学附属第三医院（广州重症孕产妇救治中心、广州柔济医院） | 2024-03-08 | — | — | CN | claimed |
| WO-2024047552-A1 | SYSTEMS AND METHODS FOR TARGETED GENOME-EDITING IN PLANTS | INDIAN COUNCIL OF AGRICULTURAL RESEARCH (IN) | 2024-03-07 | — | — | WO | claimed |
| WO-2023217280-A1 | PROGRAMMABLE ADENINE BASE EDITOR AND USES THEREOF | HUIDAGENE THERAPEUTICS CO., LTD. (CN) | 2023-11-16 | — | — | WO | claimed |
| EP-4014046-A1 | DNA REPAIR BLOOD TEST FOR PREDICTING RESPONSE OF LUNG CANCER PATIENTS TO IMMUNOTHERAPY | Yeda Research and Development Co. Ltd (IL) | 2022-06-22 | — | — | EP | claimed |
| US-20220170939-A1 | DNA REPAIR BLOOD TEST FOR PREDICTING RESPONSE OF LUNG CANCER PATIENTS TO IMMUNOTHERAPY | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-06-02 | — | — | US | claimed |
| WO-2021028909-A1 | DNA REPAIR BLOOD TEST FOR PREDICTING RESPONSE OF LUNG CANCER PATIENTS TO IMMUNOTHERAPY | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2021-02-18 | — | — | WO | claimed |
| US-20190160131-A1 | METHOD FOR CELL REJUVENATION USING ROSA ROXBURGHII FRUIT EXTRACTS | TCI CO., LTD (TW) | 2019-05-30 | — | — | US | claimed |
| EP-1579015-A4 | METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL | APPLERA CORP (US) | 2006-06-21 | — | — | EP | claimed |
| EP-1579015-A2 | METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL | Applera Corporation (US) | 2005-09-28 | — | — | EP | claimed |
| EP-1579015-A3 | METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL | Applera Corporation (US) | 2005-08-25 | — | — | EP | claimed |
| US-20040023220-A1 | Integrated method for PCR cleanup and oligonucleotide removal | APPLIED BIOSYSTEMS, LLC | 2004-02-05 | — | — | US | claimed |
| WO-2004009851-A2 | METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL | APPLERA CORPORATION (US) | 2004-01-29 | — | — | WO | claimed |
| EP-1337668-A2 | METHOD FOR DETECTING METHYLATION STATES FOR A TOXICOLOGICAL DIAGNOSTIC | Epigenomics AG (DE) | 2003-08-27 | — | — | EP | claimed |
| WO-2002040710-A2 | METHOD FOR DETECTING METHYLATION STATES FOR A TOXICOLOGICAL DIAGNOSTIC | EPIGENOMICS AG (DE) | 2002-05-23 | — | — | WO | claimed |
| EP-0934521-A1 | IN VITRO ASSAY FOR CARCINOGENS USING PHENOTYPIC TRANSFORMATION OF HUMAN CELLS | Viratest Carcinogen Monitoring, Ltd. (CA) | 1999-08-11 | — | — | EP | claimed |
| US-5763180-A | In vitro assay for carcinogens using phenotypic transformation of human cells | VIRATEST CARCINOGEN MONITORING LTD. (CA) | 1998-06-09 | — | — | US | claimed |
| WO-1998007030-A1 | IN VITRO ASSAY FOR CARCINOGENS USING PHENOTYPIC TRANSFORMATION OF HUMAN CELLS | VIRATEST CARCINOGEN MONITORING LTD. (US) | 1998-02-19 | — | — | WO | claimed |