SCHEMBL14569451

SCHEMBL14569451

Bc1ccc2onc(NCC(C)(C)c3ccccc3)c2c1OC

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 12/20 0.68
KAT7 O95251 1/20 0.30
KAT6A Q92794 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1478128 0.88 KCNA5 (0.75) KCNA5KAT7KAT6A
SCHEMBL14644963 0.88 KCNA5 (0.68) KCNA5KAT7KAT6A
SCHEMBL1478358 0.87 KCNA5 (0.67) KCNA5KAT7KAT6A
SCHEMBL1478422 0.87 KCNA5 (0.67) KCNA5KAT7KAT6A
SCHEMBL1478943 0.87 KCNA5 (0.67) KCNA5KAT7KAT6A
SCHEMBL1478871 0.81 KCNA5 (1.00) KCNA5KAT7KAT6A
SCHEMBL1478929 0.80 KCNA5 (0.58) KCNA5
SCHEMBL14644964 0.80 KCNA5 (0.58) KCNA5
SCHEMBL1478165 0.77 KCNA5 (0.75) KCNA5KAT7KAT6A
SCHEMBL1480217 0.76 KCNA5 (0.64) KCNA5KAT7KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007030582-A2 ACYCLIC IKUR INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-03-15 WO disclosed