Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993348 | 0.88 | PDGFRB (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5346355 | 0.83 | MEN1 (0.53) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5206514 | 0.80 | PDGFRB (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL908565 | 0.80 | MEN1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2PDGFRB | |
| SCHEMBL29923859 | 0.80 | MEN1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2PDGFRB | |
| SCHEMBL29848581 | 0.80 | TSHR (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21061659 | 0.80 | TSHR (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14569613 | 0.80 | ABL1 (0.42) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL15234195 | 0.76 | MAPT (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4659391 | 0.76 | MAPT (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196198-B2 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |