Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.67 |
| ▸ | FNTB | P49356 | 16/20 | 0.67 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.67 |
| ▸ | RORC | P51449 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016840 | 0.90 | FNTA (0.78) | FNTAFNTBPGGT1B | |
| SCHEMBL5023612 | 0.89 | FNTA (0.70) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL5025653 | 0.88 | FNTA (0.69) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL6303247 | 0.87 | FNTA (0.79) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL14570645 | 0.87 | FNTA (0.68) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL3502124 | 0.85 | FNTA (0.75) | FNTAFNTBPGGT1B | |
| SCHEMBL14570640 | 0.85 | FNTA (0.64) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL5023704 | 0.84 | FNTA (0.69) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL5023789 | 0.83 | FNTA (0.68) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL14570642 | 0.82 | FNTA (0.67) | FNTAFNTBPGGT1BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196094-B2 | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-03-27 | — | — | US | disclosed |
| US-7196094-B2 | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-03-27 | — | — | US | disclosed |