SCHEMBL14571345

SCHEMBL14571345

CB(O)N1CCCC1B(O)O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 18/20 0.42
▸ DPP7 Q9UHL4 12/20 0.42
▸ FAP Q12884 12/20 0.42
▸ DPP8 Q6V1X1 10/20 0.42
▸ DPP9 Q86TI2 9/20 0.42
▸ PREP P48147 7/20 0.42
▸ PITRM1 Q5JRX3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17414386 0.74 — —
SCHEMBL7941599 0.71 — —
SCHEMBL17301107 0.70 POLB (0.44) DPP4DPP7FAPDPP8DPP9
SCHEMBL29306560 0.70 DPP4 (0.33) DPP4DPP7FAPDPP8DPP9
SCHEMBL8227865 0.70 ACE (0.41) —
SCHEMBL18845583 0.70 DPP4 (0.42) DPP4DPP8DPP9PREP
SCHEMBL11990508 0.70 DPP4 (0.33) DPP4DPP7FAPDPP8DPP9
SCHEMBL11990391 0.70 ACE (0.41) —
SCHEMBL85497 0.70 ACE (0.41) —
SCHEMBL17414350 0.70 KMT2A (0.34) DPP4DPP7FAPDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070072830-A1 Methods for treating diabetes POINT THERAPEUTICS, INC. (US) 2007-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070072830-A1 Methods for treating diabetes IAPP, SLC5A2, SLC2A3 DPP4 5/4885DPP7 21/4885FAP 495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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