Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 15/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618750 | 0.86 | TTK (0.62) | TTKFLT3 | |
| SCHEMBL5617938 | 0.83 | TTK (0.55) | TTK | |
| SCHEMBL5618027 | 0.82 | TTK (0.57) | TTK | |
| SCHEMBL5618708 | 0.82 | TTK (0.54) | TTK | |
| SCHEMBL5404932 | 0.81 | TTK (0.56) | TTK | |
| SCHEMBL5618687 | 0.81 | TTK (0.56) | TTKFLT3 | |
| SCHEMBL5617920 | 0.81 | TTK (0.55) | TTK | |
| SCHEMBL5618106 | 0.81 | TTK (0.56) | TTKFLT3 | |
| SCHEMBL5618516 | 0.80 | TTK (0.59) | TTK | |
| SCHEMBL5619032 | 0.80 | TTK (0.54) | TTKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186832-B2 | Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors | SUGEN INC. (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186832-B2 | Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors | SUGEN INC. (US) | 2007-03-06 | — | — | US | disclosed |