Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.86 |
| ▸ | PPARA | Q07869 | 12/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.86 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.86 |
| ▸ | CYP4X1 | Q8N118 | 1/20 | 0.86 |
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.71 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.71 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.71 |
| ▸ | DRD2 | P14416 | 1/20 | 0.71 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.71 |
| ▸ | TACR2 | P21452 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14266901 | 1.00 | PPARG (0.86) | PPARGPPARACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2903365 | 1.00 | PPARG (0.86) | PPARGPPARACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2900857 | 0.96 | PPARG (0.91) | PPARGPPARACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2898801 | 0.93 | PPARG (1.00) | PPARGPPARACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2902603 | 0.93 | PPARG (1.00) | PPARGPPARACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2898679 | 0.93 | PPARG (1.00) | PPARGPPARACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2902266 | 0.93 | PPARG (0.77) | PPARGPPARACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2901662 | 0.91 | PPARG (1.00) | PPARGPPARACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2901702 | 0.91 | PPARG (1.00) | PPARGPPARACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL2896213 | 0.89 | PPARG (0.77) | PPARGPPARACYP2C9CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186746-B2 | Indoles having anti-diabetic activity | MERCK & CO., INC. (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186746-B2 | Indoles having anti-diabetic activity | MERCK & CO., INC. (US) | 2007-03-06 | — | — | US | disclosed |