SCHEMBL14578577

SCHEMBL14578577

[2H]/N=N\c1c(S(=O)(=O)O)cc2cc(Nc3nc(C)nc(C)n3)ccc2c1O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 2/20 0.42
▸ CARM1 Q86X55 1/20 0.42
▸ PRMT3 O60678 1/20 0.42
▸ EP300 Q09472 1/20 0.42
▸ PRMT6 Q96LA8 1/20 0.42
▸ ENPP2 Q13822 9/20 0.41
▸ CD40 P25942 1/20 0.39
▸ CD40LG P29965 1/20 0.39
▸ PHLPP2 Q6ZVD8 1/20 0.37
▸ FUT8 Q9BYC5 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ CA2 P00918 1/20 0.33
▸ CA3 P07451 1/20 0.33
▸ TNNI3 P19429 1/20 0.32
▸ TNNT2 P45379 1/20 0.32
▸ TNNC1 P63316 1/20 0.32
▸ HKDC1 Q2TB90 1/20 0.32
▸ SNCA P37840 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13715874 0.79 PRMT1 (0.44) PRMT1CARM1PRMT3EP300PRMT6
SCHEMBL14374572 0.74 MPL (0.46) PRMT1PRMT3EP300PRMT6ENPP2
SCHEMBL14578748 0.74 PRMT1 (0.41) PRMT1CARM1PRMT3EP300PRMT6
SCHEMBL13881048 0.71 PRMT1 (0.57) PRMT1CARM1PRMT3EP300PRMT6
SCHEMBL14211527 0.70 CA12 (0.44) ALDH1A1CA2CA3
SCHEMBL8823161 0.70 PHLPP2 (0.38) PRMT1CARM1PRMT3EP300PRMT6
SCHEMBL11671160 0.69 PRMT1 (0.68) PRMT1CARM1PRMT3EP300PRMT6
SCHEMBL14578566 0.69 CARM1 (0.35) PRMT1CARM1
SCHEMBL3691645 0.69 FUT8 (0.69) PRMT1CARM1PRMT3EP300PRMT6
SCHEMBL3691652 0.69 FUT8 (0.69) PRMT1CARM1PRMT3EP300PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183409-B2 Basic mono- and bisazo compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2007-02-27 — — US disclosed
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