SCHEMBL14579696

SCHEMBL14579696

COc1ccc2c(c1)CCc1cc(OC(=O)c3ccc4ccc(C(C)=O)cc4c3)ccc1-2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.50
▸ MEN1 O00255 4/20 0.50
▸ CASP3 P42574 1/20 0.50
▸ SENP8 Q96LD8 1/20 0.50
▸ SENP7 Q9BQF6 1/20 0.50
▸ SENP6 Q9GZR1 1/20 0.50
▸ MAPT P10636 6/20 0.44
▸ RAB9A P51151 4/20 0.44
▸ KDM4E B2RXH2 4/20 0.44
▸ GLA P06280 2/20 0.44
▸ GAA P10253 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ NPC1 O15118 3/20 0.44
▸ NFKB1 P19838 1/20 0.44
▸ NFKB2 Q00653 1/20 0.44
▸ RELA Q04206 1/20 0.44
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14579698 0.97 KMT2A (0.47) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL14579688 0.89 KMT2A (0.53) KMT2AMEN1MAPTRAB9AKDM4E
SCHEMBL14579726 0.88 MAPT (0.54) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL14579682 0.87 KMT2A (0.63) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL14579692 0.86 KMT2A (0.51) KMT2AMEN1MAPTRAB9AKDM4E
SCHEMBL14579680 0.84 KDM4E (0.60) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL14579694 0.84 KMT2A (0.49) KMT2AMEN1MAPTRAB9AKDM4E
SCHEMBL14579691 0.84 KMT2A (0.51) KMT2AMAPTRAB9AKDM4EGLA
SCHEMBL14579690 0.81 MAPT (0.55) KMT2AMAPTRAB9AKDM4ETDP1
SCHEMBL14579668 0.80 KMT2A (0.60) KMT2AMEN1CASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7175955-B2 Electrophotographic photoreceptor, electrophotographic process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-02-13 — — US disclosed
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