Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542557 | 0.88 | KDM4E (0.44) | AKR1B1KMT2A | |
| SCHEMBL11285815 | 0.83 | TSHR (0.47) | AKR1B1KMT2AMEN1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL16796889 | 0.81 | KMT2A (0.39) | AKR1B1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL5720933 | 0.80 | KMT2A (0.51) | AKR1B1KMT2AMEN1CYP2D6LMNA | |
| SCHEMBL31701959 | 0.80 | KMT2A (0.51) | AKR1B1KMT2AMEN1CYP2D6LMNA | |
| SCHEMBL381519 | 0.80 | KMT2A (0.51) | AKR1B1KMT2AMEN1CYP2D6LMNA | |
| SCHEMBL6074933 | 0.80 | AKR1B1 (0.50) | AKR1B1KMT2ACYP2C9MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL19470580 | 0.80 | CTSA (0.37) | KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19470579 | 0.80 | CTSA (0.37) | KMT2ASMN1; SMN2 | |
| SCHEMBL25253132 | 0.79 | CTSA (0.47) | KMT2AMEN1GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032474-A1 | Use of a compound of formula 1 for making a pharmaceutical composition | BIONDI RICARDO M | 2007-02-08 | — | — | US | disclosed |
| US-20070032474-A1 | Use of a compound of formula 1 for making a pharmaceutical composition | BIONDI RICARDO M | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032474-A1 | Use of a compound of formula 1 for making a pharmaceutical composition | CYP7A1, UGT1A1, CYP2F1 | AKR1B1 173/4885KMT2A 4178/4885CYP2C9 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.