SCHEMBL14580673

SCHEMBL14580673

c1cnc(-c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2ccccc2-3)nc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 15/20 0.47
CLK4 Q9HAZ1 3/20 0.36
DYRK1A Q13627 1/20 0.36
ADRB2 P07550 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9920518 1.00 PDK2 (0.47) PDK2CLK4DYRK1AADRB2KDM4E
SCHEMBL9920507 1.00 PDK2 (0.47) PDK2CLK4DYRK1AADRB2KDM4E
SCHEMBL12390430 0.93 PDK2 (0.41) PDK2CLK4DYRK1AADRB2
SCHEMBL14731178 0.92 PDK2 (0.43) PDK2
SCHEMBL12390417 0.90 PDK2 (0.43) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL19383442 0.88 PDK2 (0.46) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL15977790 0.87 PDK2 (0.39) PDK2
SCHEMBL14580672 0.87 KMT2A (0.43) PDK2KDM4EMEN1MAPTKMT2A
SCHEMBL29603105 0.86 PDK2 (0.39) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL14580681 0.86 PDK2 (0.39) PDK2KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070042220-A1 Compound having spiro bond, material for luminescent coating formation and organic electroluminescence element including the same IDEMITSU KOSAN CO., LTD. (JP) 2007-02-22 US disclosed
US-20070042220-A1 Compound having spiro bond, material for luminescent coating formation and organic electroluminescence element including the same IDEMITSU KOSAN CO., LTD. (JP) 2007-02-22 US disclosed