Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287151 | 0.88 | MEN1 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL14582943 | 0.83 | SMN1; SMN2 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL4287200 | 0.83 | MEN1 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL14583107 | 0.82 | MEN1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL14107074 | 0.80 | KMT2A (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL14107075 | 0.80 | KMT2A (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL14107073 | 0.80 | KMT2A (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL13704081 | 0.80 | MEN1 (0.62) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL13704082 | 0.80 | MEN1 (0.68) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL14583092 | 0.80 | MEN1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026024-A2 | BENZODIAZEPINES AS HCV INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-03-08 | — | — | WO | disclosed |