SCHEMBL14585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14634	0.93	SYK (0.40)	LPAR1SYKTHRBHDAC4HDAC6
	SCHEMBL13831064	0.90	USP2 (0.44)	LPAR1ALDH1A1THRBUSP2CYP3A4
	SCHEMBL13720242	0.90	LPAR1 (0.51)	LPAR1LPAR2LPAR3HDAC1HDAC8
	SCHEMBL14592	0.89	LPAR1 (0.44)	LPAR1SYKLPAR2LPAR3ALDH1A1
	SCHEMBL6147	0.87	LPAR1 (0.45)	LPAR1LPAR2LPAR3ALDH1A1HTT
	SCHEMBL10980	0.87	LPAR1 (0.38)	LPAR1LPAR3THRBHDAC4HDAC6
	SCHEMBL14736	0.86	MAPT (0.36)	LPAR1LPAR2LPAR3THRBHDAC4
	SCHEMBL14570	0.86	FFAR1 (0.47)	LPAR1LPAR2LPAR3THRBCYP3A4
	SCHEMBL13830939	0.85	IP6K1 (0.43)	LPAR1ALDH1A1USP2CYP3A4ADRA2C
	SCHEMBL2337996	0.85	LPAR1 (0.46)	LPAR1SYKLPAR2LPAR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.