Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HMGCR | P04035 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8756199 | 0.87 | GAA (0.59) | GAAHSPA5KMT2AHMGCRALDH1A1 | |
| SCHEMBL14586752 | 0.85 | GAA (0.57) | GAAKMT2AALDH1A1TSHRCYP1A2 | |
| SCHEMBL14586753 | 0.80 | GAA (0.51) | GAAKMT2AALDH1A1TSHRCYP1A2 | |
| SCHEMBL15142812 | 0.79 | HSPA5 (0.57) | GAAHSPA5KMT2AHMGCRALDH1A1 | |
| SCHEMBL12894651 | 0.79 | GAA (0.52) | GAAHSPA5KMT2AHMGCRALDH1A1 | |
| SCHEMBL12443050 | 0.78 | HSPA5 (0.51) | GAAHSPA5KMT2AHMGCRALDH1A1 | |
| SCHEMBL17433310 | 0.78 | HSPA5 (0.51) | GAAHSPA5KMT2AHMGCRALDH1A1 | |
| SCHEMBL11795971 | 0.78 | HSPA5 (0.70) | GAAHSPA5KMT2AHMGCRALDH1A1 | |
| SCHEMBL25955774 | 0.78 | GAA (0.64) | GAAHSPA5KMT2AHMGCRALDH1A1 | |
| SCHEMBL12443045 | 0.77 | HSPA5 (0.47) | GAAHSPA5KMT2AHMGCRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032581-A1 | Additive mixtures | CIBA CORPORATION | 2007-02-08 | — | — | US | disclosed |