Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5648457 | 0.99 | HTR2C (0.54) | HTR2CMCHR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5648007 | 0.90 | HTR2C (0.56) | HTR2CMCHR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5645579 | 0.86 | MCHR1 (0.73) | HTR2CMCHR1MAPTSMN1; SMN2 | |
| SCHEMBL27611493 | 0.84 | HTR2C (0.58) | HTR2CMCHR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5645354 | 0.83 | MCHR1 (0.78) | HTR2CMCHR1 | |
| SCHEMBL5649248 | 0.83 | HTR2C (0.48) | HTR2CMCHR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5647726 | 0.83 | MCHR1 (0.77) | HTR2CMCHR1 | |
| SCHEMBL14587881 | 0.80 | MCHR1 (0.57) | HTR2CMCHR1 | |
| Hydrochloric Acid SCHEMBL5648012 | 0.79 | MCHR1 (0.56) | HTR2CMCHR1 | |
| SCHEMBL14587880 | 0.76 | MCHR1 (0.56) | HTR2CMCHR1MAPTTDP1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |