Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.66 |
| ▸ | FNTB | P49356 | 10/20 | 0.66 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.66 |
| ▸ | RORC | P51449 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657946 | 0.92 | FNTA (0.69) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL1683566 | 0.91 | FNTA (0.79) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL5023160 | 0.90 | FNTA (0.77) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL3553255 | 0.89 | FNTA (0.72) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL3981343 | 0.89 | FNTA (0.71) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL13501479 | 0.89 | FNTA (0.71) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL3974455 | 0.87 | FNTA (0.69) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL14570644 | 0.86 | FNTA (0.70) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL5022749 | 0.85 | FNTA (0.68) | FNTAFNTBPGGT1BRORC | |
| SCHEMBL5658274 | 0.85 | FNTA (0.65) | FNTAFNTBPGGT1BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173040-B2 | Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derinazoline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-06 | — | — | US | disclosed |