Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 19/20 | 0.69 |
| ▸ | CHUK | O15111 | 11/20 | 0.69 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021015 | 0.84 | IKBKB (0.67) | IKBKBCHUKGRM1 | |
| SCHEMBL5655531 | 0.82 | IKBKB (1.00) | IKBKBCHUK | |
| SCHEMBL14589117 | 0.81 | IKBKB (0.49) | IKBKBCHUK | |
| SCHEMBL14589121 | 0.79 | IKBKB (0.47) | IKBKBCHUK | |
| SCHEMBL14589118 | 0.74 | IKBKB (0.70) | IKBKBCHUK | |
| SCHEMBL5660641 | 0.72 | IKBKB (0.65) | IKBKBCHUK | |
| SCHEMBL5659200 | 0.70 | IKBKB (0.50) | IKBKBCHUKGRM1 | |
| SCHEMBL5939971 | 0.70 | IKBKB (0.72) | IKBKBCHUK | |
| SCHEMBL5657595 | 0.68 | IKBKB (0.75) | IKBKBCHUK | |
| SCHEMBL14014381 | 0.68 | IKBKB (0.48) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176214-B2 | Imidazo-fused oxazolo[4,5-β]pyridine and imidazo-fused thiazolo[4,5-β]pyridine based tricyclic compounds and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-13 | — | — | US | disclosed |