Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 1.00 |
| ▸ | CHUK | O15111 | 13/20 | 0.76 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | BTK | Q06187 | 1/20 | 0.57 |
| ▸ | ITK | Q08881 | 1/20 | 0.57 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14589474 | 0.87 | IKBKB (0.77) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589480 | 0.86 | IKBKB (0.79) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL5658578 | 0.86 | IKBKB (1.00) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589490 | 0.86 | IKBKB (0.79) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL5657205 | 0.86 | IKBKB (1.00) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL5659008 | 0.85 | IKBKB (0.77) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589488 | 0.85 | IKBKB (0.77) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589405 | 0.85 | IKBKB (0.80) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589482 | 0.84 | IKBKB (0.76) | IKBKBCHUKCDK2BTKITK | |
| SCHEMBL14589319 | 0.84 | IKBKB (0.76) | IKBKBCHUKCDK2BTKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176214-B2 | Imidazo-fused oxazolo[4,5-β]pyridine and imidazo-fused thiazolo[4,5-β]pyridine based tricyclic compounds and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-13 | — | — | US | disclosed |
| US-7176214-B2 | Imidazo-fused oxazolo[4,5-β]pyridine and imidazo-fused thiazolo[4,5-β]pyridine based tricyclic compounds and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-13 | — | — | US | disclosed |