Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | ABL2 | P42684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13649848 | 0.83 | ADORA1 (0.60) | ADORA1ADORA2ANPSR1RXFP1MEN1 | |
| SCHEMBL4252331 | 0.82 | ADORA1 (0.71) | ADORA1ADORA2AEGFR | |
| SCHEMBL4259626 | 0.81 | ADORA1 (0.73) | ADORA1ADORA2ALMNA | |
| SCHEMBL3872580 | 0.80 | ADORA1 (0.58) | ADORA1ADORA2ANPSR1RXFP1MEN1 | |
| SCHEMBL4252889 | 0.80 | ADORA1 (0.67) | ADORA1ADORA2ANPSR1RXFP1EGFR | |
| SCHEMBL4250469 | 0.79 | ADORA1 (0.70) | ADORA1ADORA2AEGFR | |
| SCHEMBL4259710 | 0.79 | ADORA1 (0.70) | ADORA1ADORA2ANPSR1MEN1KMT2A | |
| SCHEMBL4253955 | 0.78 | ADORA1 (0.69) | ADORA1ADORA2ANPSR1MEN1KMT2A | |
| SCHEMBL4261130 | 0.78 | ADORA1 (0.76) | ADORA1ADORA2A | |
| SCHEMBL15425807 | 0.78 | ADORA1 (0.81) | ADORA1ADORA2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160890-B2 | Compounds specific to adenosine A3 receptor and uses thereof | OSI PHARMACEUTICALS, INC. (US) | 2007-01-09 | — | — | US | disclosed |