Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592796 | 0.91 | TLR7 (0.51) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL14592837 | 0.89 | TLR7 (0.48) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL14592832 | 0.89 | TLR7 (0.47) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL14592712 | 0.88 | TLR7 (0.47) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL14592715 | 0.88 | TLR7 (0.47) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL14592821 | 0.87 | TLR7 (0.46) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL14592750 | 0.86 | TLR7 (0.46) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL14592826 | 0.86 | TLR7 (0.52) | TLR7 | |
| SCHEMBL14592703 | 0.86 | TLR7 (0.51) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL14592806 | 0.86 | TLR7 (0.46) | TLR7LMNAPOLBHRH2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157453-B2 | Urea substituted imidazoquinolines | 3M INNOVATION PROPERTIES COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-7157453-B2 | Urea substituted imidazoquinolines | 3M INNOVATION PROPERTIES COMPANY (US) | 2007-01-02 | — | — | US | disclosed |