Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD5 | P21918 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592764 | 0.88 | TLR7 (0.49) | TLR7HTR2AADRA1ALMNAPOLB | |
| SCHEMBL5746829 | 0.88 | TLR7 (0.48) | TLR7HTR2AADRA1ALMNAPOLB | |
| SCHEMBL14592796 | 0.87 | TLR7 (0.51) | TLR7HTR2AADRA1ALMNAPOLB | |
| SCHEMBL14592782 | 0.87 | TLR7 (0.48) | TLR7HTR2AADRA1ALMNAPOLB | |
| SCHEMBL14592762 | 0.86 | KMT2A (0.52) | TLR7HTR2AADRA1ALMNAPOLB | |
| SCHEMBL14592756 | 0.85 | TLR7 (0.44) | TLR7HTR2AADRA1ALMNAPOLB | |
| SCHEMBL14592781 | 0.85 | KDM4E (0.48) | TLR7HTR2AADRA1ALMNAPOLB | |
| SCHEMBL14592713 | 0.85 | TLR7 (0.48) | TLR7HTR2AADRA1ALMNAPOLB | |
| SCHEMBL14592744 | 0.83 | TLR7 (0.44) | TLR7HTR2AADRA1ALMNAPOLB | |
| SCHEMBL14592753 | 0.83 | TLR7 (0.53) | TLR7HTR2AADRA1ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157453-B2 | Urea substituted imidazoquinolines | 3M INNOVATION PROPERTIES COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-7157453-B2 | Urea substituted imidazoquinolines | 3M INNOVATION PROPERTIES COMPANY (US) | 2007-01-02 | — | — | US | disclosed |