⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812846 | 0.65 | — | — | |
| SCHEMBL1539042 | 0.59 | — | — | |
| SCHEMBL6156694 | 0.59 | — | — | |
| SCHEMBL5670 | 0.56 | — | — | |
| SCHEMBL6349880 | 0.56 | — | — | |
| SCHEMBL620133 | 0.56 | — | — | |
| SCHEMBL118349 | 0.56 | — | — | |
| SCHEMBL1963922 | 0.56 | — | — | |
| SCHEMBL3156856 | 0.56 | — | — | |
| SCHEMBL5549683 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729917-A | Combination therapy using AKR1C3 activating compounds and immune checkpoint inhibitors | 深圳艾欣达伟医药科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| EP-2718291-A1 | BENZOQUINOLIZIDINE DERIVATIVES, METHOD FOR PREPARING SAME, AND THERAPEUTIC USES THEREOF | Pierre Fabre Medicament (FR) | 2014-04-16 | — | — | EP | claimed |
| WO-2012168368-A1 | BENZOQUINOLIZIDINE DERIVATIVES, METHOD FOR PREPARING SAME, AND THERAPEUTIC USES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2012-12-13 | — | — | WO | claimed |
| JP-62167713-A | — | — | None | — | — | JP | disclosed |
| JP-62174065-A | — | — | None | — | — | JP | disclosed |
| JP-10175975-A | — | — | None | — | — | JP | disclosed |
| CN-110325534-B | Substituted imidazoquinolines as NLRP3 modulators | 先天肿瘤免疫公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117098819-A | Cell culture system, method and use thereof | 周美吟 | 2023-11-21 | — | — | CN | disclosed |
| EP-2841433-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL CO (JP) | 2017-06-21 | — | — | EP | disclosed |
| CN-103958516-B | Azetidine compounds, compositions and they are as the purposes of the inhibitor of solvable Epoxide hydrolase | 霍夫曼-拉罗奇有限公司 | 2016-08-24 | — | — | CN | disclosed |
| US-9380782-B2 | Tetrazolinone compounds and its use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-0328001-A1 | Benzoxazinone compounds and herbicidal composition containing the same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-08-16 | — | — | EP | disclosed |
| JP-S62174065-A | OXAZOLIDINEDIONE DERIVATIVE AND PRODUCTION THEREOF | SAGAMI CHEM RES CENTER | 1987-07-30 | — | — | JP | disclosed |
| JP-S62167713-A | HERBICIDE | SAGAMI CHEM RES CENTER | 1987-07-24 | — | — | JP | disclosed |
| US-4663475-A | Ethylenically unsaturated N-(halosulfonyl) carbamyl monomers | THE DOW CHEMICAL COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| US-4500675-A | Stable dispersions of polymers in polyfunctional compounds having a plurality of active hydrogens | THE DOW CHEMICAL COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| US-4226876-A | MITICIDES | BURROUGHS WELLCOME CO. (US) | 1980-10-07 | — | — | US | disclosed |
| US-3988155-A | CYANINE SENSITIZING DYES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-26 | — | — | US | disclosed |
| US-3986878-A | SILVER HALIDE PHOTOGRAPHIC EMULSION | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-19 | — | — | US | disclosed |
| US-3985563-A | Silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |